Pamrevlumab,一种抗结缔组织生 - 肺纤维化专科治疗医院

TUhjnbcbe - 2021/1/30 2:53:00

北京荨麻疹治疗好医院 http://baidianfeng.39.net/a_zhiliao/210116/8595950.html

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Pamrevlumab,ananti-connectivetissuegrowthfactortherapy,foridiopathicpulmonaryfibrosis(PRAISE):aphase2,randomised,double-blind,placebo-controlledtrial（LancetRespMed,IF:22.9）

RicheldiL,FernándezPérezER,CostabelU,etal.Pamrevlumab,ananti-connectivetissuegrowthfactortherapy,foridiopathicpulmonaryfibrosis(PRAISE):aphase2,randomised,double-blind,placebo-controlledtrial.TheLancetRespiratoryMedicine;8:25-33.

Correspondenceto:ProfLucaRicheldi,UnitàOperativaComplessadiPneumologia,FondazionePoliclinicoUniversitarioA.GemelliIRCCS,UniversitàCattolicadelSacroCuore,Rome,Italyluca.richeldi

policlinicogemelli.it

Summary背景

BackgroundConnectivetissuegrowthfactor(CTGF)isasecretedglycoproteinthathasacentralroleintheprocessoffibrosis.Thisstudywasdesignedtoassessthesafety,tolerability,andefficacyofpamrevlumab(FG-),afullyre